Table 1B:
Diabetes sample baseline characteristics.
| Overall Sample (N=224) | DM Event (N=21) | No DM Event (N=203) | p-value | |
|---|---|---|---|---|
| Median age, years (IQR) | 54.50 (44.00–63.00) | 56.00 (46.00–67.50) | 54.00 (43.00–63.00) | 0.32 |
| Male, N (%) | 96 (42.9%) | 13 (61.9%) | 83 (40.9%) | 0.064 |
| Caucasian, N (%) | 210 (89.3%) | 19 (90.5%) | 181 (89.2%) | 0.85 |
| Median baseline BMI, kg/m2 (IQR) | 26.26 (23.02–30.84) | 28.45 (23.15–32.04) | 26.10 (23.01–30.68) | 0.21 |
| Median baseline VAT volume, cm3 (IQR) | 47.09 (26.00–72.51) | 66.34 (23.32–102.94) | 46.88 (26.27–71.25) | 0.23 |
| Baseline HTN, N (%) | 69 (30.8%) | 6 (28.6%) | 63 (31.0%) | 0.82 |
| Baseline hyperlipidemia, N (%) | 58 (25.9%) | 7 (33.3%) | 51 (25.1%) | 0.41 |
| Fasting glucose > 100 mg/dL within 2 years prior to imaging, N (%) | 109 (48.7%) | 8 (61.9%) | 96 (47.3%) | 0.20 |
| Median maximum fasting glucose < 2 years before imaging, mg/dL (IQR) | 102.00 (90.00–112.00) | 116.00 (98.00–128.00) | 101.00 (89.25–109.75) | 0.003 |
| Median fasting glucose at time of imaging, mg/dL (IQR) | 98.00 (90.00–107.00) | 104.50 (97.50–131.00) | 97.00 (90.00–106.00) | 0.006 |
| Pre-DM, N (%) | 113 (50.4%) | 15 (71.4%) | 6 (28.6%) | 0.043 |
| Current smoking, N (%) | 17 (7.6%) | 2 (9.5%) | 15 (7.4%) | 0.73 |
| History of cancer, N (%) | 200 (89.3%) | 20 (95.2%) | 180 (88.7%) | 0.35 |
| History of chemotherapy or radiation, N (%) | 186 (83.0%) | 20 (95.2%) | 166 (81.8%) | 0.12 |
| Median air pollution, particulate matter ≤2.5 μm, μg/m3 (IQR) | 5.61 (4.83–6.13) | 5.76 (4.83–6.06) | 5.61 (4.83–6.13) | 0.95 |
| Median neighborhood income, $ (IQR) | 80399 (61919–101597.75) | 92300 (71467.50–111612) | 79540 (61619–100286) | 0.084 |
| Median local crime rate (IQR) | 21.69 (14.16–34.22) | 16.50 (10.76–35.93) | 22.46 (14.50–34.22) | 0.51 |
| Median average transportation noise exposure, dBA (IQR) | 35–40 (<35–50) | 45–50 (35–55) | 35–40 (<35–50) | 0.019 |
| Median amygdalar activity (IQR) | 0.79 (0.73–0.85) | 0.84 (0.80–0.91) | 0.78 (0.72–0.84) | 0.005 |
Air pollution available in 384 subjects, crime in 304 subjects, and amygdalar activity in 238 subjects.
Abbreviations: BMI-body mass index, DM-diabetes mellitus, HTN-hypertension, IQR- interquartile range, VAT-visceral adipose tissue