Table 1.
Patient characteristics.
| Characteristics | No. (%) of patients | No. (%) of patients | No. (%) of patients | p |
|---|---|---|---|---|
| Group | All | CEA kin. ≤0.05 | CEA kin. >0.05 | |
| Frequency | N = 192 | N = 133 | N = 25 | |
| Median age (range), years | 68 (27–87) | 67 (37–87) | 70 (27–86) | 0.87 |
| Sex (n = 192) | 0.74 | |||
| Male | 108 (56.2) | 74 (55.6) | 13 (52) | |
| Female | 84 (43.8) | 59 (44.4) | 12 (48) | |
| ECOG PS (n = 179) | 0.36 | |||
| 0 | 88 (49.2) | 67 (53.6) | 9 (42.9) | |
| ≥1 | 91 (50.8) | 58 (46.4) | 12 (57.1) | |
| Tumour location (n = 191) | 0.39 | |||
| Right colon | 60 (31.4) | 35 (26.5) | 7 (28) | |
| Left colon | 89 (46.6) | 65 (49.2) | 15 (60) | |
| Rectum | 42 (22.0) | 32 (24.2) | 3 (12) | |
| Primary tumour in place (n = 192) | 0.92 | |||
| No | 106 (55.2) | 76 (57.1) | 14 (56) | |
| Yes | 86 (44.8) | 57 (42.9) | 11 (44) | |
| Synchronous metastasis (n = 192) | 0.79 | |||
| No | 59 (30.7) | 39 (29.3) | 8 (32) | |
| Yes | 133 (69.3) | 94 (70.7) | 17 (68) | |
| Metastatic sites | NA | |||
| Liver | 156 (48.3) | 109 (46.2) | 22 (57.9) | |
| Lung | 86 (26.6) | 68 (28.8) | 10 (26.3) | |
| Nodes | 46 (14.2) | 33 (14) | 4 (10.5) | |
| Peritoneal | 18 (5.6) | 10 (4.2) | 2 (5.3) | |
| Others | 17 (5.3) | 16 (6.8) | 0 (0) | |
| No. of metastatic sites (n = 192) | 0.69 | |||
| 1 | 91 (47.4) | 58 (43.6) | 12 (48) | |
| ≥2 | 101 (52.6) | 75 (56.4) | 13 (52) | |
| Line of chemotherapy (n = 192) | 0.37 | |||
| First line | 134 (69.8) | 89 (66.9) | 19 (76) | |
| ≥Second line | 58 (30.2) | 44 (33.1) | 6 (24) |
NA not applicable, PS performance status.