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. 2021 Aug 30;11:17385. doi: 10.1038/s41598-021-96429-x

Table 2.

The frequency of the specific alleles and genotypes of the UGT1A1*28 variant in the group of women with osteopenia and controls.

Genotypes Osteopenia Control OR 95% CI p
Observed value n (%) Expected value % Observed value n (%) Expected value (%)
6/6 43 (39.5) 36.7 88 (37.8) 40.3 1.07 0.65–1.75 0.049
6/7 46 (42.2) 47.8 120 (51.5) 46.4 0.69 0.42–1.12
7/7 20 (18.3) 15.5 25 (10.7) 13.3 1.87 0.93–3.70
Total 109 (100%) 100.00 233 (100%) 100.00

The expected value was calculated in accordance with the Hardy–Weinberg equilibrium (HWE). HWE equilibrium test was used to obtain the exact p value.

OR odds ratio.