Effect of treatment with Pc (50, 100 mg/kg) on lipid peroxides levels in (a) cerebral cortex; ###p <0.001—sham versus ICV-STZ, ***p <0.001–ICV-STZ versus RIV, **p <0.01—ICV-STZ versus Pc 50, ***p <0.001—ICV-STZ versus Pc 100, (b) hippocampus; ###p <0.001—sham versus ICV-STZ, ***p <0.001—ICV-STZ versus RIV, ***p <0.001—ICV-STZ versus Pc 100 and (c) nitrite levels in plasma of ICV-STZ administered rats; ###p <0.001—sham versus ICV-STZ, ***p <0.001—ICV-STZ versus RIV, *p <0.05—ICV-STZ versus Pc 100. Values were expressed as mean ± SEM. The intergroup variation was measured by one way ANOVA followed by Tukey’s test using Graphpad prism 5.0 (Graphpad Software Inc, CA, USA)