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. 2021 Aug 25;14(8):dmm048995. doi: 10.1242/dmm.048995

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© 2021. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — Mitochondrial function and glycolytic activity in HP SK-FBs. (A) OCR in mito-stress test, basal and after consecutive injections of OL, FCCP and Rot/AA (****P<0.0001, two-way ANOVA with Tukey's multiple comparison test). (B) ECAR in glycolysis-stress test, basal and after sequential injections of Glu, OL and 2-DG (****P<0.0001, two-way ANOVA with Tukey's multiple comparison test). (C) Quantification of basal OCR, ATP-linked respiration and maximal respiration (*P<0.05, Wilcoxon test). (D) Quantification of glycolytic capacity and glycolysis (*P<0.05, Wilcoxon test). (E) Representation of the XF cell energy phenotype. Treated (4-OHT) and untreated (CT) Cre(−) (n=3) and Cre(+) (n=3) SK-FBs are shown (mean±s.e.m.).