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Nick DNA-binding kinetics of ligase IIIα/XRCC1 complex in the presence of ATP. The real-time binding kinetics of ligase IIIα/ATP to nick DNA in the absence (A) and presence (B) of XRCC1. C, table shows the effect of XRCC1 on the equilibrium binding constant (KD), the association (kon) and dissociation (koff) rates of ligase IIIα/ATP/nick DNA catalytic ternary complex.
