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. 2021 Aug 23;32:102790. doi: 10.1016/j.nicl.2021.102790

Table 1.

Demographic and clinical characteristics.

HC (mean/sd or count/percent) UD (mean/sd or count/percent) t-test or chi-squared test HC vs. UD
N 47 (54.7%) 39 (45.3%)
Gender (number females) 36 (76.6%) 29 (74.6%) χ2(1) = 0, p = 1
UD diagnoses (MDD/PDD) na 26/13 na
Age (years) 28.55 (6.15) 29.07 (6.88) t(84) = -0.37, p = 0.71
IQ (NART) 106.72 (6.24) 110.2 (7.49) t(84) = -2.35, p = 0.02
Illness Onset (year of age) na 15.05 (5.02) na
Lifetime episodes of depression na 3.25 (1.5) na
Current depression severity (HRSD-25) 1.74 (2.16) 12.69 (6.77) t(84) = −10.48, p < 0.01
Lifetime depression (MOODS-SR) 2.15 (2.27) 18.41 (4.36) t(84) = −22.21, p < 0.01
Number taking Antidepressants na 22 (56.4%) na
Number taking Mood stabilizers na 3 (7.7%) na
Number taking Antipsychotics na 1 (2.6%) na
Number taking Benzodiazepines na 5 (12.8%) na
Number taking Stimulants na 3 (7.7 %) na
Mean number of psychotropic medications na 1.05 (1.12) na
Mean total medication load na 1.33 (1.53) na
Number with comorbid diagnoses na 27 (69.2%) na

Note: Comparison of demographic and clinical characteristics between healthy controls (HC) and individuals with Unipolar Depression (UD). Tests were run as t-tests or chi-squared tests, as specified. Bold = p < 0.05. na = not applicable.