Table 2.

The comparison of the T1w/T2w ratio in selected parcels in individuals with UD vs. HC.

Parcel	t	p	p-FDR	Selection Frequency	Extended Description
Left 11 l	−3.056	0.003	0.032	100.00	BA 11 (orbital and polar frontal)
Left 7PC	3.081	0.003	0.032	100.00	BA 7 (superior parietal cortex)
Left MST	2.892	0.005	0.032	100.00	Medial superior temporal area
Left p10p	−2.536	0.013	0.038	100.00	BA 10 (frontopolar margin of orbital prefrontal cortex)
Right FOP2	−2.574	0.012	0.038	100.00	Frontal Opercular area 2 (posterior opercular cortex)
Right FFC	−2.534	0.013	0.038	100.00	Fusiform face complex
Left STSdp	−2.036	0.045	0.071	99.95	Auditory association cortex
Right TE2p	2.928	0.004	0.032	99.89	Lateral temporal complex
Left LBelt	−2.713	0.008	0.038	99.35	Lateral belt complex (auditory)
Left a24pr	−3.003	0.004	0.032	99.29	Ventral anterior cingulate cortex.
Right 7AL	−2.512	0.014	0.038	99.18	BA 7 (superior parietal cortex)
Left d23ab	−2.157	0.034	0.060	95.53	Ventral posterior cingulate cortex
Left 6a	−2.291	0.025	0.054	95.25	BA 6 (premotor subdivisions)
Left 24dv	−2.556	0.012	0.038	59.36	Ventral anterior cingulate cortex.
Right V3A	1.795	0.076	0.097	47.52	Visual area V3A
Left V4t	−1.650	0.103	0.117	39.44	Visual area V4t
Right LBelt	−2.122	0.037	0.061	33.99	Lateral belt complex (auditory)
Left p32	2.179	0.032	0.060	33.66	BA 32 (pregenual anterior cingulate)
Right PH	2.152	0.034	0.060	22.97	Posterior temporal visual region
Right POS2	1.921	0.058	0.082	19.97	Parieto-occipital sulcus area 2
Right FOP1	−1.816	0.073	0.096	19.31	Frontal Opercular area 1 (posterior opercular cortex)
Right RI	1.559	0.123	0.135	18.22	RetroInsular cortex
Left 47 m	−1.735	0.086	0.102	15.77	BA 47 (orbital part of inferior frontal gyrus)
Left s32	−2.442	0.017	0.040	12.22	BA 32 (subgenual anterior cingulate)
Left MT	2.176	0.033	0.060	11.95	Middle temporal area
Left RI	−2.520	0.014	0.038	11.78	RetroInsular cortex
Right OP1	−1.237	0.220	0.220	8.89	Parietal operculum (secondary somatosensory cortex)
Left PeEc	−1.429	0.157	0.162	6.98	Perirhinal ectorhinal cortex
Left FOP4	−2.489	0.015	0.038	6.66	Frontal Opercular area 4 (posterior opercular cortex)
Right RSC	−2.009	0.048	0.072	6.22	RetroSplenial complex
Right 52	1.493	0.139	0.148	6.06	BA 52 (parainsular)
Right 7Pm	1.913	0.059	0.082	5.18	BA 7 (superior medial parietal cortex)
Right 5 m	−1.777	0.079	0.097	3.98	BA5 (paracentral lobule)

The association of UD with the T1w/T2w ratio in the n = 33 selected variables. Tests were run as linear regressions, testing the association of case/control status with the T1w/T2w ratio, controlling for age, sex, and IQ. Positive t-values indicate greater T1w/T2w ratio (and, consequently, greater cortical myelin level) in UD vs. HC. We report both uncorrected and FDR-corrected p-values.