Table 3.

Effects of BS on renal function and proteinuria

Variables	6 months pre-BS	3 months pre-BS	Baseline	Month 3	Month 6	Month 12	Month 24
Serum creatinine ( mg/dL)	1 ± 0.4	1.1 ± 0.5	1.1 ± 0.4	1 ± 0.4	1 ± 0.4*	1 ± 0.4	1 ± 0.4
eGFR (MDRD, mL/min)	104.8 ± 49.6	89.9 ± 39.5	96.8 ± 49.8	93 ± 42.5	92.9 ± 40.8	84.9 ± 44.5	81.2 ± 44.7
eGFR (CKD-EPI, mL/min)	108.9 ± 48.5	95.2 ± 41.5	97.3 ± 47.8	96.4 ± 43.2	95.9 ± 37.9	86.6 ± 40.2	80.5 ± 40.1
mGFR (iohexol, mL/min)	102.23 ± 44.2	90.9 ± 35.8	94 ± 43.7	67.5 ± 32.9*	72.7 ± 36.6*	65.6 ± 35.5*	79.6 ± 44.5*
Proteinuria (g/24 h)	2.1 ± 1.51	2.3 ± 1.6	2.6 ± 2.9	1.1 ± 0.9*	0.9 ± 0.6*	0.9 ± 0.9*	0.6 ± 0.4*
Median (IQR)	1.6 (0.9–3.7)	1.7 (1–3.6)	1.6 (1–2.7)	0.9 (0.3–1.8)	0.7 (0.4–1.2)	0.6 (0.3–0.9)	0.5 (0.3–0.9)
Proteinuria reduction (%)	–	–	–	49.3 ± 27.2	54.9 ± 26.4	60.7 ± 16.8	63.7 ± 28.2
UACR (mg/g)	1140 ± 1096	1095 ± 859	1912 ± 2233	650.3 ± 871*	478.8 ± 623*	582.4 ± 884*	479.7 ± 540*
Median (IQR)	601 (411–1863)	790 (317–1882)	1004 (554–2078)	296 (139–599)	266 (97–636)	194 (81–671)	220 (87–860)
UACR reduction (%)	–	–	–	61.7 ± 25.5	69.3 ± 23.2	70.6 ± 23.8	mean ± SD

^*Values are presented as mean ± SD unless stated otherwise.P < 0.05 versus baseline.

UACR: urinary albumin:creatinine ratio.