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IL-2-induced expression of IL-2Rα is normal in IFN-γR-deficient mice. T lymphocytes from IFN-γR-deficient (−/−) or wild-type (WT) mice were stimulated for 24 h with ConA in the presence of the IL-2-blocking MAbs (ConA primed), and IL-2 was then added for the indicated times. (A) FACS analysis of IL-2Rα expression on T cells. (B) Bandshift assay with 3 μg of nuclear extracts incubated with the FcγRI probe for 15 min.
