FIG. 6.

IL-2-induced in vivo protection of IL-2rE sites follows a temporal pattern. (A) In vivo footprinting analysis was performed with ConA-primed cells or primed cells cultured further with or without IL-2 for the indicated times. (B) The phosphorimager histograms of the footprints obtained with the different populations are compared to the one from ConA-primed cells. The results shown are representative of three experiments. Arrowheads indicate partial protection of guanine bases. Nucleotide positions are marked to the right of panel A.