Table 2.

Public relative search topics rising in “osteoporosis.”

Rank	Worldwide	Australia	New Zealand	Canada	Ireland	UK	USA
	Search topics (% rising)	Search topics (% rising)	Search topics (% rising)	Search topics (% rising)	Search topics (% rising)	Search topics (% rising)	Search topics (% rising)
1	Denosumab (breakouta)	Bone (breakout)	Bone (breakout)	Osteoarthritis (breakout)	Bone (breakout)	Bone density (breakout)	Risk factor (breakout)
2	FRAXb (breakout)	Calcium (breakout)	Osteoarthritis (breakout)	Guideline (breakout)	Osteoarthritis (breakout)	Osteopenia (breakout)	Denosumab (breakout)
3	Bone tumor (breakout)	Bone density (breakout)	Calcium (breakout)	Denosumab (breakout)	Irish Osteoporosis Society (breakout)	Dual-energy X-ray absorptiometry (breakout)	Teriparatide (breakout)
4	Hip fracture (breakout)	Preventive healthcare (breakout)	Vitamin D (breakout)	Bisphosphonate (breakout)	Calcium (breakout)	Osteomalacia (breakout)	Ibandronic acid (breakout)
5	Osteomalacia (1100)	Osteopenia (breakout)	Osteomalacia (breakout)	Risk factor (breakout)	Osteopenia (breakout)	FRAX (breakout)	Osteomyelitis (breakout)
6	Bone density (550)	Rheumatoid arthritis (breakout)	Bone density (breakout)	Risedronic acid (breakout)	Royal Osteoporosis Society (breakout)	Osteoarthritis (750)	Osteogenesis imperfecta (breakout)
7	Risk factor (450)	Risk factor (breakout)	Osteopenia (breakout)	Bone (650)	None	Calcium (300)	Mineral (breakout)
8	Osteoarthritis (400)	Denosumab (breakout)	Osteoporosis (40)	Osteoporosis (190)	None	Preventive healthcare (250)	Osteoarthritis (950)
9	Arthritis (250)	Osteoarthritis (300)	None	Preventive healthcare (180)	None	Osteoporosis (150)	Risk (450)
10	Osteopenia (140)	Osteoporosis (190)	None	Bone density (170)	None	Bone (60)	Bone (200)

^a“Breakout” represents that the search term grew by more than 5000% compared with previous period.

^bFRAX: fracture risk assessment tool.