Table 3.

Lipid profiles and insulin parameters for ITT and per-protocol

	ITT analyses			Per-protocol analyses
	intervention, N = 164	control, N = 132	p value	pp-compliant, N = 55	pp-non-compliant, N = 109	p value
T2 CHOL, mmol/L, mean±SD	5.75±1.04	5.57±0.90	0.2041	5.65±0.86	5.81±1.13	0.4587
T3 CHOL, mmol/L, mean±SD	6.04±1.11	5.96±1.08	0.5797	6.07±1.03	6.07±1.17	0.9815
Δ, mmol/L, mean±SD	0.38±0.49	0.39±0.63	0.8898	0.43±0.44	0.37±0.52	0.5687
T2 TG, mmol/L, mean±SD	2.81±0.87	2.91±1.00	0.4319	2.88±0.85	2.80±0.89	0.6282
T3 TG, mmol/L, mean±SD	3.56±1.19	3.71±1.92	0.4461	3.88±1.77	3.52±1.23	0.1655
Δ, mmol/L, mean±SD	0.68±0.78	0.80±1.41	0.4584	0.72±0.78	0.65±0.77	0.6821
T2 HDL, mmol/L, mean±SD	1.68±0.35	1.62±0.30	0.1702	1.58±0.27	1.72±0.37	0.0567
T3 HDL, mmol/L, mean±SD	1.63±0.31	1.61±0.31	0.5143	1.55±0.24	1.67±0.32	0.0254*
Δ, mmol/L, mean±SD	−0.03±0.18	−0.02±0.17	0.6733	0±0.13	−0.04±0.20	0.2213
T2 LDL, mmol/L, mean±SD	2.93±0.84	2.78±0.76	0.1908	2.87±0.72	2.98±0.92	0.5433
T3 LDL, mmol/L, mean±SD	3.08±1.12	3.01±0.93	0.6348	2.99±0.82	3.13±1.26	0.5131
Δ, mmol/L, mean±SD	0.25±0.90	0.17±0.43	0.4587	0.17±0.37	0.29±1.06	0.5449
T2 FINS, μIU/mL, mean±SD	104.61±41.06	106.77±59.40	0.8426	101.33±29.46	108.67±43.02	0.4879
T2 HOMA-IR, mean±SD	3.96±4.53	4.30±6.60	0.6324	3.21±5.28	3.63±4.96	0.1952

Δ, Lipid change from the 2nd to 3rd trimester. ITT, intention to treat; T2, 2nd trimester; T3, 3rd trimester; CHOL, cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FINS, fasting insulin; HOMA-IR, homeostasis model assessment-insulin resistance.

^*Values are statistically significant at p < 0.05.