Table 3.

Impact of anthropometric and functional parameters on metabolic response to exercise

	RERpeak		ΔRER		ΔRER%
	R	p value	r	p value	r	p value
Age, years	Ns		−0.299	0.006	−0.294	0.006
BMI, kg/m2	Ns		Ns		Ns
Waist, cm	Ns		Ns		−0.246	0.028
FM, kg	0.254	0.02	0.219	0.04		Ns
FFM, kg	0.305	0.005	Ns		Ns
GAUC min, mmol/L	−0.311	0.014	−0.387	0.002	−0.378	0.002
IAUC min, mU/L	Ns		Ns		Ns
HOMAIR	Ns		−0.240	0.038	−0.232	0.046
ISIm	Ns		Ns		Ns
FPG, mmol/L	Ns		−0.215	0.048	Ns
METs	Ns		Ns		Ns
VO2, mL/min/kg	0.276	0.011	0.244	0.024	0.216	0.048

Univariate correlation analyses, performed for PwO, analyzing the metabolic response to maximal exercise. RERpeak, ΔRER, and ARER% were tested for those parameters that showed significant differences between Ob-N, Ob-preDM, and Ob-T2DM. Correlation is expressed as Pearson's R coefficient; p value is considered significant when <0.05. FM, fat mass; FFM, fat free mass; FPG, fasting plasma glucose; G_AUC, glucose area under curve; I_AUC, insulin area under curve; ISI_m, insulin sensitivity Matsuda index; METs, peak metabolic equivalent of tasks; RER, respiratory exchange ratio; RERpeak, respiratory exchange ratio at peak of exercise; ARER, RERpeak-RERrest; PwO, people with obesity; Ob-N, people with obesity and normal glycemic status; Ob-preDM, people with obesity and prediabetes; Ob-T2DM, people with obesity and type 2 diabetes; HOMA_IR, Homeostasis Model Assessment index.