Table 2.
Area under the receiver operating characteristics curve (AUC), sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), negative likelihood ratio (LR-) and positive likelihood ratio (LR+) for all lesions were calculated using a cut-off ADC of ≥ 1.5*10−3 mm2/s. In addition, mass and non-mass lesions and lesions with a maximum diameter equal to and below or above 10 mm were considered separately.
| AUC (95%CI) |
Sensitivity (95%CI) |
Specificity (95%CI) |
NPV (95%CI) |
PPV (95%CI) |
LR- (95%CI) |
LR+ (95%CI) |
|
|---|---|---|---|---|---|---|---|
| Total | 400/414 | 92/282 | 92/106 | 400/590 | |||
| 0.784 (0.752-0.814) | 96.6% (94.3-98.1) | 32.6% (28.2-37.4) | 86.8% (83.1-89.8) | 67.8% (63.0-72.2) | 0.1 (0.06-0.18) | 1.43 (1.32-1.56) | |
| Mass lesions | 343/352 | 57/160 | 57/66 | 343/446 | |||
| 0.816 (0.779-0.848) | 97.4% (95.3-98.7) | 35.6% (31.0-40.5) | 86.4% (82.6-89.4) | 76.9% (72.5-80.8) | 0.07 (0.04-0.14) | 1.51 (1.35-1.70) | |
| Non-mass lesions | 57/62 | 35/122 | 35/40 | 57/144 | |||
| 0.671 (0.598-0.738) | 91.9% (88.8-94.3) | 28.7% (24.4-33.4) | 87.5% (83.8-90.5) | 39.6% (34.9-44.5) | 0.28 (0.12-0.68) | 1.29 (1.13-1.47) | |
| Size ≦10 mm | 85/87 | 41/133 | 41/43 | 85/177 | |||
| 0.748 (0.685-0.804) | 97.7% (95.6-98.8) | 30.8% (26.5-35.6) | 95.3% (92.7-97.1) | 48.0% (43.1-53.0) | 0.07 (0.02-0.30) | 1.41 (1.26-1.59) | |
| Size >10 mm | 315/327 | 51/149 | 51/63 | 315/413 | |||
| 0.828 (0.791-0.861) | 96.3% (93.9-97.8) | 34.2% (29.7-39.0) | 81.0% (76.8-84.6) | 76.3% (71.8-80.2) | 0.11 (0.06-0.20) | 1.46 (1.30-1.65) |
95%CI: 95% confidence interval