Table 2.

BRRM uptake at 10 and 20 years by risk group and additional factors.

		BRRM		Competing risks (breast cancer/death)
		10 year % (95%CI)	20 year % (95%CI)	10 year % (95%CI)	20 year % (95%CI)
Risk group	25–29%	2.39 (1.69–3.38)	2.92 (2.09–4.09)	4.33 (3.31–5.65)	7.92 (6.37–9.84)
	30–39%	3.66 (3.03–4.41)	4.78 (3.98–5.73)	4.58 (3.85–5.44)	8.73 (7.48–10.18)
	40–49%	7.39 (5.96–9.14)	9.04 (7.26–11.24)	5.13 (3.95–6.67)	11.25 (9.05–13.96)
	BRCA1/2	45.00 (40.18–50.11)	47.67 (42.40–53.24)	9.11 (6.55–12.59)	14.05 (10.08–19.41)
Mother BC	No FDR died BC	5.67 (5.05–6.37)	6.73 (5.98–7.58)	4.55 (3.96–5.22)	8.72 (7.70–9.88)
	Mother BC death	10.22 (8.52–12.25)	11.68 (9.78–13.93)	5.53 (4.27–7.16)	10.72 (8.71–13.17)
Sister BC	Sister death	10.49 (7.60–14.38)	11.66 (8.57–15.77)	6.06 (3.90–9.35)	11.19 (1.93–15.64)
Age entry	<30	8.77 (6.89–11.13)	11.93 (9.44–15.03)	1.50 (0.90–2.80)	5.05 (3.29–7.71)
	30–39	8.46 (7.46–9.59)	9.42 (8.32–10.67)	3.93 (3.22–4.78)	8.36 (7.05–9.89)
	40–49	4.41 (3.59–5.41)	5.33 (4.34–6.54)	5.67 (4.70–6.83)	10.07 (8.53–11.87)
	50+	3.79 (2.64–5.43)	3.79 (2.64–5.43)	8.88 (6.91–11.39)	13.78 (10.95–17.28)
Biopsy	No	6.34 (5.73–7.02)	7.40 (6.69–8.19)	5.22 (4.64–5.88)	9.93 (8.95–11.02)
	Yes	9.24 (7.05–12.07)	10.88 (8.37–14.09)	0.40 (0.10–1.61)	2.09 (0.10–4.43)
Parity	Nulliparous	5.21 (4.20–6.45)	7.34 (6.60–8.16)	4.48 (3.51–5.70)	7.42 (5.93–9.27)
	Parous	6.32 (5.07–7.87)	8.49 (7.64–9.42)	4.97 (4.35–5.69)	9.82 (8.75–11.01)
Era	<1994	4.50 (3.04–6.65)	5.79 (4.08–8.18)	6.23 (4.47–8.66)	15.96 (12.98–19.55)
	1994–2003	5.89 (5.00–6.92)	6.97 (5.98–8.11)	5.57 (4.71–6.59)	9.39 (8.22–10.73)
	2003-04/2013	7.86 (6.82–9.04)	9.13 (7.77–10.79)	4.48 (3.69–5.43)	5.46 (4.47–6.67)
	≥ May 2013	14.17 (4.82–37.7)	14.17 (4.82–37.7)	0.87 (0.05–1.57)	0.87 (0.05–1.57)

RRM – Risk reducing mastectomy, BC – breast cancer, FDR – first degree relative.