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. 2001 Jan 22;2001(1):CD001519. doi: 10.1002/14651858.CD001519

Comparison 1. Cabergoline versus Bromocriptine.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 UPDRS ADL scores (part II)     Other data No numeric data
2 UPDRS motor scores (part III)     Other data No numeric data
3 Hoehn and Yahr stage     Other data No numeric data
4 Schwab and England scale     Other data No numeric data
5 Clinicians global impression (number much or very much improved) 3 784 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.01 [0.76, 1.33]
6 Levodopa dose reduction (mg) 4 909 Mean Difference (IV, Fixed, 95% CI) 6.00 [‐21.79, 33.79]
7 Off time reduction (hours) 4 612 Mean Difference (IV, Fixed, 95% CI) 0.29 [‐0.10, 0.68]
8 Adverse events ‐ Nausea 5 1048 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.99 [0.73, 1.35]
9 Adverse events ‐ Postural hypotension 5 1048 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.74 [0.49, 1.11]
10 Adverse events ‐ Hallucinations 5 1048 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.34 [0.88, 2.06]
11 Adverse events ‐ Confusion 4 835 Peto Odds Ratio (Peto, Fixed, 95% CI) 2.02 [1.09, 3.76]
12 Adverse event ‐ Dyskinesia 5 1048 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.57 [1.05, 2.35]
13 Adverse events ‐ Insomnia 5 1048 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.95 [0.58, 1.54]
14 Adverse events ‐ Sleep disorder 3 793 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.35 [0.82, 2.21]
15 Adverse events ‐ Vivid dreams 1 44 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.0 [0.06, 16.52]
16 Adverse events ‐ Somnolence 4 1006 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.97 [0.55, 1.73]
17 All cause withdrawal rate 5 1071 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.87 [0.63, 1.20]