| 1 UPDRS ADL scores (part II) |
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Other data |
No numeric data |
| 2 UPDRS motor scores (part III) |
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Other data |
No numeric data |
| 3 Hoehn and Yahr stage |
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Other data |
No numeric data |
| 4 Schwab and England scale |
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Other data |
No numeric data |
| 5 Clinicians global impression (number much or very much improved) |
3 |
784 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.01 [0.76, 1.33] |
| 6 Levodopa dose reduction (mg) |
4 |
909 |
Mean Difference (IV, Fixed, 95% CI) |
6.00 [‐21.79, 33.79] |
| 7 Off time reduction (hours) |
4 |
612 |
Mean Difference (IV, Fixed, 95% CI) |
0.29 [‐0.10, 0.68] |
| 8 Adverse events ‐ Nausea |
5 |
1048 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.99 [0.73, 1.35] |
| 9 Adverse events ‐ Postural hypotension |
5 |
1048 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.74 [0.49, 1.11] |
| 10 Adverse events ‐ Hallucinations |
5 |
1048 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.34 [0.88, 2.06] |
| 11 Adverse events ‐ Confusion |
4 |
835 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
2.02 [1.09, 3.76] |
| 12 Adverse event ‐ Dyskinesia |
5 |
1048 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.57 [1.05, 2.35] |
| 13 Adverse events ‐ Insomnia |
5 |
1048 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.95 [0.58, 1.54] |
| 14 Adverse events ‐ Sleep disorder |
3 |
793 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.35 [0.82, 2.21] |
| 15 Adverse events ‐ Vivid dreams |
1 |
44 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.0 [0.06, 16.52] |
| 16 Adverse events ‐ Somnolence |
4 |
1006 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.97 [0.55, 1.73] |
| 17 All cause withdrawal rate |
5 |
1071 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.87 [0.63, 1.20] |