Summary of findings 2. Table of descriptive data.
ID | Country of Study | Setting | Years of education | Language(s) of tests | MMSE Diagnostic Threshold | Target condition | Definition of dementia | Follow‐up | Definition MCI |
Buchhave 2008 | Sweden | Memory clinic | Not provided | Unclear | 28/29 | ADD | DSM III‐R + NINCDS‐ADRDA | 5,2 years (4 to 6.8) | Petersen criteria |
Conde‐Sala 2012 | Spain | Memory clinic | 50% had attended school for six to eight years | Spanish | 21/22 | ADD | DSM‐IV‐TR or NINCDS‐ADRDA | 5 years | European AD consortium (EADC) criteria for MCI |
Chopard 2009 | France | Memory clinic | ≥ 12 years of education = 8.5% | Unclear | 26/27 | All‐cause dementia | IADLs scores affected + CDR = 0.5 to 1 and DSM‐IV + CDR = 1 + plus NINCDS‐ADRDA or NINDS‐AIREN or criteria for DLB or Lund and Manchester criteria | 14.9 months (± 4.5) | Presence of cognitive complaints + no daily activities affected + CDR = 0.5 + no DSM‐IV criteria for dementia |
Devanand 2008 | USA | Memory clinic | Converters = 14 (4.7) Non‐converters= 15.4 (4.1) | English | Not provided | ADD | DSM‐IV + NINCDS‐ADRDA | 3 years | Petersen criteria |
Meguro 2007a | Japan | Population sample | 8.3 years | Japanese | 17/18 for 6 or less years of education 20/21 for 7 to 8 years 23/24 for 10 or more years | All‐cause dementia | DSM‐IV + CDR = 1 + plus NINCDS‐ADRDA or NINDS‐AIREN or criteria for DLB or Lund and Manchester criteria | 5 years | CDR = 0.5 |
Meguro 2007b | Japan | Population sample | No provided | Japanese | 17/18 for 6 or less years of education 20/21 for 7 to 8 years 23/24 for 10 or more years | All‐cause dementia | DSM‐IV + CDR = 1 | 7 years | CDR = 0.5 |
Modrego 2005 | Spain | Outpatient clinic | No provided | Spanish | 26/27 from 35; 29/30 from 35 | ADD | NINCDS‐ADRDA | 1 to 5 years | Petersen criteria for amnestic MCI |
Modrego 2013 | Spain | Outpatient clinic | Converters = elementary: 78.9%; high school: 17.5%; university: 3.5% Non‐converters = elementary: 79.2%; high school: 12.5%; university: 8.3% | Spanish | 30/31 from 35 | ADD | NINCDS‐ADRDA | 2 years (1 to 4) | CDR = 0.5 + BDRS < 4 |
Palmqvist 2012 | Sweden | Memory clinic | No provided | Swedish | 26/27; 9/10 for O&R subscale | ADD | NINCDS‐ADRDA | 5.9 years (3.2 to 8.8) | Petersen criteria |
Pozueta 2011 | Spain | Memory clinic | % primary school: Pr‐AD = 66.6 S‐MCI = 71.42 | Spanish | 26/27 | ADD | Unclear | 2 years | Petersen criteria |
Xu 2002 | USA | Outpatient research clinic | Non‐dementia = 12.17 (5.23) All dementias = 10.06 (6.11) | English | 26/27 for dementia or AD; 25/26 for VaD | All‐cause dementia, ADD VaD |
NINCDS‐ADRDA or NINDS‐AIREN or criteria for dementia by Lewy bodies or Lund and Manchester criteria or NINDS‐SPSP | 3.89 (2 to 17) | Unclear |
See 'Characteristics of included studies' for more detailed study descriptors.
Abbreviations: ADD = Alzheimer´s Disease Dementia; CDR = Clinical Dementia Rating; DSM = Diagnostic and Statistical Manual of Mental Disorders; ICD‐10 = International Statistical Classification of Diseases and Related Health Problems 10th Revision; MCI = Mild cognitive Impairment; MMSE = Mini‐Mental State Examination; NINCDS‐ADRDA = National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer´s Disease and Related Disorders Association; NINDS‐AIREN = National Institute of Neurological Disorders and Stroke and Association Internationales pour la Recherche et l´Ensignement en Neurosciences; O&R = MMSE´s Orientation and Recall items; Pr‐AD = Prodormal AD; USA = United States of America; VaD = Vascular Dementia.