1. Characteristics of patients included in comparison 1.
| Neo CT n (%) | No neo CT n (%) | Total (N=2074) | |
| Age (years) | |||
| <35 | 134 (13) | 139 (13) | 273 |
| 35‐50 | 491 (48) | 454 (43) | 945 |
| 51‐65 | 329 (32) | 372 (35) | 701 |
| >65 | 72 (7) | 82 (8) | 154 |
| Unknown | 0 (0) | 1 (<1) | 1 |
| Stage* | |||
| IB | 126 (12) | 130 (12) | 256 |
| II | 291 (28) | 320 (31) | 611 |
| III | 418 (41) | 418 (40) | 836 |
| IV | 27 (3) | 28 (3) | 55 |
| Unknown | 164 (16) | 152 (15) | 316 |
| Histology | |||
| Squamous | 958 (93) | 976 (93) | 1934 |
| Adenocarcinoma | 6 (1) | 9 (1) | 15 |
| Other | 54 (5) | 58 (6) | 112 |
| Unknown | 8 (1) | 5 (<1) | 13 |
| Grade† | |||
| Well differentiated | 105 (10) | 97 (9) | 202 |
| Moderately differentiated | 299 (29) | 334 (32) | 633 |
| Poorly differentiated | 302 (29) | 285 (27) | 587 |
| Unknown | 320 (31) | 332 (32) | 652 |
| Performance status‡ | |||
| 0 | 671 (65) | 656 (63) | 1327 |
| 1 | 230 (22) | 240 (23) | 470 |
| 2 | 55 (5) | 57 (5) | 112 |
| 3 | 14 (1) | 11 (1) | 25 |
| Unknown | 56 (5) | 84 (8) | 140 |
| Lymph node status§ | |||
| Uninvolved | 288 (28) | 280 (27) | 568 |
| Involved | 121 (12) | 149 (14) | 270 |
| Unknown | 617 (60) | 619 (59) | 1236 |
| N.B. Percentages may not add up to 100% because of rounding | |||
| * Data missing completely for 1 trial †Data missing completely for 3 trials and for a large proportion of patients in 1 trial ‡Data missing completely for 1 trial and for a large proportion of patients in 2 trials §Data missing completely for 8 trials and for most patients in 2 trials |