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. 2004 Apr 19;2004(2):CD001774. doi: 10.1002/14651858.CD001774.pub2

MRC CeCa.

Methods RCT
 1991‐1995
Participants 48 (0*) FIGO stage IB‐IVA
Interventions CT RT or S vs RT or S
CT: CDDP 50mg/m2 MTX 100 mg/m2 Folinic acid 15mg po/6h 30 after start of CDDP and MTX. Every 14 days for 3 cycles.
RT: External beam 46Gy in 23F over 32 days. Intracavitary 20Gy
Outcomes Survival
 Disease‐free survival
 Locor‐regional disease‐free survival
 Metastases‐free survival
Notes Treatment comparison 1
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk A ‐ Adequate