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. 2006 Jul 19;2006(3):CD004348. doi: 10.1002/14651858.CD004348.pub2

Keitz 2001.

Methods Randomized controlled trial
Participants 214 subjects (19 died, 15 lost to follow‐up) 
 General Medicine Clinic (GMC): 
 58.7% Male 
 11.9% White 
 85.3% African‐American 
 Mean age: 35.0 +/‐ 8.2 
 Infectious Disease Clinic (IDC): 
 63.8% Male 
 20.0% White 
 71.4% African‐American 
 Mean age‐ 34.3% +‐ 9.0
Interventions CLINIC, HOSPITAL OR WARD VOLUME OF HIV/AIDS PATIENTS: 
 General Medicine Clinic staffed by internists ‐ <50 HIV patients 
 vs 
 Infectious Disease Clinic (staffed by ID specialists ‐ 1100 HIV patients)
Outcomes PROPORTION OF PATIENTS ON ARVs: 
 GMC: 
 Use of 0 ‐ 20% 
 Use of 1 ‐ 47% 
 Use of 2 ‐ 20% 
 Use of 3 ‐ 13% 
 IDC: 
 Use of 0 ‐ 24% 
 Use of 1 ‐ 41% 
 Use of 2 ‐ 21% 
 Use of 3 ‐ 14% 
 PROPORTION OF PATIENTS ON INDICATED PROPHYLAXIS: 
 (MAC/PCP) 
 GMC: 
 MAC ‐ 66% 
 Appropriate PCP‐ 93% 
 IDC: 
 MAC ‐ 56% 
 Appropriate PCP ‐ 98% 
 HEALTHCARE UTLIZATION: 
 a) Visits to home clinic 
 GMC ‐ 4.31 visits 
 (+/‐ 3.81) 
 IDC ‐ 4.41 visits (+/‐ 4.69) 
 b) ER Visits 
 GMC ‐ 1.58 (+/‐ 3.03) 
 IDC ‐ 0.71 (+/‐ 1.49) 
 p=.01 (p<.05 after adjustment) 
 c) HOSPITALIZ‐ 
 ATION 
 GMC ‐ 33% 
 IDC ‐ 25% 
 p=.11 (p=.08 after adjustment) 
 d) LENGTH OF HOSPITAL STAY 
 GMC ‐ 9 (+/‐ 7 days) 
 IDC ‐ 5.3 (+/‐ 3 days)p=.01 (p=.05 after adjustment) 
 PSYCHOSOCIAL OUTCOME: HRQL Scale (max score is 100) 
 a) physical 
 GMC 
 before 42.1 +/‐ 12.2 
 after ‐ 35.7 +/‐ 11.1 
 IDC 
 before 42.8 +/‐ 13.3 
 after 37.2 +/‐ 11.7 
 b) mental 
 GMC 
 before 
 42.4 +/‐ 12.5 
 after 
 37.8 +/‐ 11.8 
 IDC 
 before 
 40.2 +/‐ 12.7 
 after 37.2 +/‐ 11.7
Notes Difference btw healthcare utlization btw the two groups
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk D ‐ Not used