Safran 1995.

Methods	Controlled clinical trial
Participants	349 subjects a) Control group: 17% Female 23% Non‐white Mean age ‐ 42 years b) Intervention group: 17% Female 17% Non‐white Average age 35.4 years.
Interventions	HEALTH INFORMATION SYSTEMS: Computer prompts vs. Control
Outcomes	PATIENT MORTALITY: Estimated survival rate at 1 year: a) Control = 88% b) Intervention = 91% p = 0.19 PROPORTION OF PTS PROGRESSING TO AIDS (diagnosis of PCP): a) Control = 21 b) Intervention = 20 p = 0.09 PROPORTION OF PTS ON ARVS (# of days til start) a) Control = 43 days b) Intervention = 7 days PROPORTION OF PTS ON INDICATED PROPHYLAXIS (# of days til prophylaxis) a) Control = 122 days b) Intervention = 11 days p = <.0001 HEALTHCARE UTILIZATION 1 or more hospitalizations a) Control 44% b) Intervention 35% p = .47 2) Visits to primary care providers p = .29 3) ED Visits p = .24
Notes	Computer‐based patient records can be an effective vehicle for delivering care guidelines.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	D ‐ Not used