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. Author manuscript; available in PMC: 2022 Aug 26.
Published in final edited form as: J Phys Chem B. 2021 Aug 15;125(33):9547–9556. doi: 10.1021/acs.jpcb.1c04052

Figure 8.

Figure 8.

The probability of interactions of PIP2 with selected residues of the TRPV5 channel along the reaction coordinate. An interaction is considered when any atoms of the residue side chain are within 6 A from any of the phosphate groups of PIP2. The probability is estimated from the entire ensemble of Milestoning trajectories.