Comparison 1. ACEi versus no treatment.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Serum creatinine	2	42	Mean Difference (IV, Random, 95% CI)	‐0.02 [‐0.14, 0.09]
2 GFR [mL/min/1.73 m²]	3	103	Mean Difference (IV, Random, 95% CI)	‐3.41 [‐15.83, 9.01]
3 Doubling of serum creatinine	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
4 Total kidney volume	2	42	Mean Difference (IV, Random, 95% CI)	‐42.50 [‐115.68, 30.67]
5 Albuminuria	3	103	Std. Mean Difference (IV, Random, 95% CI)	‐0.12 [‐0.51, 0.26]
6 Systolic blood pressure	2	42	Mean Difference (IV, Random, 95% CI)	‐5.44 [‐14.26, 3.38]
7 Diastolic blood pressure	2	42	Mean Difference (IV, Random, 95% CI)	‐4.96 [‐8.88, ‐1.04]
8 Mean arterial pressure	1	61	Mean Difference (IV, Random, 95% CI)	‐5.0 [‐6.29, ‐3.71]