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. 2021 Aug 12;11:672126. doi: 10.3389/fonc.2021.672126

Table 1.

Clinical Characteristics of the Study Population.

Characteristic CK19 negative (151) CK19 positive (106) p-value
Age 0.266
≥50 112 71
<50 39 35
Gender 0.009
Male 141 87
Female 10 19
Differentiation 0.719
Good 63 41
Poor 88 65
Tumor size 0.600
≥5 cm 66 42
<5 cm 85 64
Tumor number 0.711
Single 93 62
Multiple 58 44
Microvascular invasion 0.089
Yes 54 50
No 97 56
Macrovascular invasion 0.581
Yes 18 16
No 133 90
Lymph node metastasis 0.688
Yes 2 3
No 149 103
Cirrhosis 0.651
Yes 106 78
No 45 28
HBV infection 0.699
Yes 136 93
No 15 13
PLT 135.50 ± 59.40 149.10 ± 75.17 0.107
ALB 39.96 ± 5.66 40.79 ± 5.97 0.255
ALT 50.58 ± 101.03 50.16 ± 63.79 0.970
AST 60.45 ± 158.22 55.16 ± 77.12 0.750
GGT 114.74 ± 158.89 93.17 ± 85.55 0.204
FBG 5.46 ± 1.68 5.76 ± 2.15 0.215
TB 19.60 ± 19.55 26.24 ± 50.65 0.145
DB 10.03 ± 16.31 15.08 ± 43.95 0.198
IB 9.58 ± 6.69 11.19 ± 8.72 0.096
Serum AFP 2,666.07 ± 11,635.29 4,312.00 ± 14,029.66 0.307
Serum CEA 3.14 ± 1.77 3.37 ± 4.59 0.588
Serum CA19-9 84.60 ± 840.43 19.54 ± 33.05 0.427

HBV, hepatitis B virus; PLT, platelet; ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; FBG, fasting blood glucose; TB, total bilirubin; DB, direct bilirubin; IB, indirect bilirubin; AFP, α-fetoprotein; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9.

Bold values indicate statistically different at P values < 0.05.