| UPDRS ADL scores (part II) | |
|---|---|
| Study | |
| Guttman 1997 | Average of off and on phase: Median improvement on pramipexole 2.5 v placebo 0.5 (p<0.0002) |
| Lieberman 1997 | Off phase: Mean improvement on pramipexole 24% v placebo 5% (p<0.0001) On phase: Mean improvement on pramipexole 18% v placebo 1% (p<0.004) Average of off and on phase: Mean improvement on pramipexole 22% v placebo 4% (p<0.0001) |
| Pinter 1999 | Average of off and on phase: Mean improvement on pramipexole 4.4 v placebo 1.2 (p=0.005) |
| Wermuth 1998 | Details not available but a significant improvement on pramipexole compared with placebo (p=0.0015) |
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