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. 2021 Apr 19;2021(4):CD013792. doi: 10.1002/14651858.CD013792.pub2

Comparison 2. Threatened miscarriage: Dydrogesterone versus placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
2.1 Live birth 1 406 Risk Ratio (M‐H, Fixed, 95% CI) 0.98 [0.89, 1.07]
2.2 Miscarriage (defined as delivery before 24 weeks of gestation) 1 406 Risk Ratio (M‐H, Fixed, 95% CI) 0.90 [0.55, 1.47]
2.3 Preterm birth (defined as birth before 37 weeks of gestation) 1 334 Risk Ratio (M‐H, Fixed, 95% CI) 0.87 [0.40, 1.88]
2.4 Stillbirth 1 406 Risk Ratio (M‐H, Fixed, 95% CI) 0.33 [0.01, 8.13]
2.5 Congenital abnormalities 1 406 Risk Ratio (M‐H, Fixed, 95% CI) 0.71 [0.23, 2.21]
2.6 Adverse drug events 1 406 Risk Ratio (M‐H, Fixed, 95% CI) 2.00 [0.18, 21.88]