| Methods |
2‐arm placebo‐controlled randomised trial. |
| Participants |
160 women were randomised in a hospital setting in Iran. The population comprised women with clinical symptoms of threatened abortion (bleeding, spotting, and uterine cramps before the 20th week of pregnancy) and singleton pregnancy. Exclusion criteria comprised women with systemic diseases, maternal hypertension before or during pregnancy, uterine tenderness, genetic or anatomical defects of the fetus, renal or cardiac diseases, genital tract anomalies of the mother and diabetes and those patients who had used a progestational drug during pregnancy, prior to being recruited into the study. |
| Interventions |
200 mg vaginal progesterone, twice daily for 1 week versus placebo. |
| Outcomes |
The study recorded the following outcomes relevant for this review: miscarriage and preterm birth. |
| Notes |
Evidence of trial documentation and data requested from the corresponding author, who replied but did not answer all of our queries or provide the requested documentation or data. The trial was retrospectively registered and no explanation for this was provided. |
