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OME decreases the protein expression levels of the proliferation-related gene PCNA. (A) The TE1 and KYSE150 cell lines were treated with 0, 100 and 300 µM OME and the protein expression levels of PCNA were determined by western blot analysis. (B) The results were semi-quantitatively analyzed using gray-scale analysis **P<0.01. OME, omeprazole; PCNA, proliferating cell nuclear antigen; ESCC, esophageal squamous cell carcinoma.
