Goncalves 2011.
Study characteristics | |||
Patient Sampling | Cross‐sectional study of consecutive memory clinic attenders attending with an informant | ||
Patient characteristics and setting | Participants were referred by their primary care physicians Memory clinic, city hospital in Brisbane Australia, n = 204 |
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Index tests | IQCODE 16 item, English language | ||
Target condition and reference standard(s) | Clinical diagnosis of dementia using DSM‐IV‐TR criteria including IQCODE result | ||
Flow and timing | Of 243 potential subjects, 208 attended with an informant. A further 4 were excluded due to missing cognitive test data, final sample n = 204 Index test and initial assessment performed together; clinical assessment by psychiatrist performed 2 weeks later with knowledge of all results and reference standard determined at that point |
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Comparative | |||
Notes | |||
Methodological quality | |||
Item | Authors' judgement | Risk of bias | Applicability concerns |
DOMAIN 1: Patient Selection | |||
Was a consecutive or random sample of patients enrolled? | Yes | ||
Was a case‐control design avoided? | Yes | ||
Did the study avoid inappropriate exclusions? | Yes | ||
Could the selection of patients have introduced bias? | Low risk | ||
Are there concerns that the included patients and setting do not match the review question? | Low concern | ||
DOMAIN 3: Reference Standard | |||
Is the reference standards likely to correctly classify the target condition? | Yes | ||
Could the reference standard, its conduct, or its interpretation have introduced bias? | High risk | ||
Are there concerns that the target condition as defined by the reference standard does not match the question? | Low concern | ||
DOMAIN 4: Flow and Timing | |||
Was there an appropriate interval between index test and reference standard? | Yes | ||
Were all patients included in the analysis? | No | ||
Could the patient flow have introduced bias? | Low risk |