Hancock 2009.

Study characteristics
Patient Sampling	Consecutive new patient referrals to memory clinic attending with an informant
Patient characteristics and setting	Memory clinics in a psychiatric hospital and cognitive function clinic based in a regional neuroscience centre in the UK, n = 144
Index tests	IQCODE 16 item, English language
Target condition and reference standard(s)	Clinical dementia diagnosis using DSM‐IV
Flow and timing	144 included, no figures to quote how many ineligible over study period Index test performed independently from clinical assessment and not used to assess reference standard. Both tests performed on same day
Comparative
Notes
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	Yes
Was a case‐control design avoided?	Yes
Did the study avoid inappropriate exclusions?	Yes
Could the selection of patients have introduced bias?		Low risk
Are there concerns that the included patients and setting do not match the review question?			Low concern
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	Yes
Could the reference standard, its conduct, or its interpretation have introduced bias?		Low risk
Are there concerns that the target condition as defined by the reference standard does not match the question?			Low concern
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Yes
Were all patients included in the analysis?	Yes
Could the patient flow have introduced bias?		Low risk