Harwood 1997.

Study characteristics
Patient Sampling	Random sample of urgent admissions in over‐65s. Sample was determined by assigning a number on a card to each admission and selecting half of the cards each day at random
Patient characteristics and setting	Unscheduled admissions (aged > 65 years) admitted to an acute medical unit of a UK teaching hospital in Oxford (n = 201)
Index tests	IQCODE 16 item, English language
Target condition and reference standard(s)	Clinical dementia diagnosis using DSM‐III‐R
Flow and timing	Of 223 potential participants, 13 died prior to assessment or were excluded due to being 'too ill' to participate, 7 declined consent, 2 were excluded due to absence at time of assessment ‐ result in n = 201 participants Index test and reference standard conducted contemporaneously, but not blinded
Comparative
Notes
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	Yes
Was a case‐control design avoided?	Yes
Did the study avoid inappropriate exclusions?	Yes
Could the selection of patients have introduced bias?		Low risk
Are there concerns that the included patients and setting do not match the review question?			Low concern
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	Yes
Could the reference standard, its conduct, or its interpretation have introduced bias?		Unclear risk
Are there concerns that the target condition as defined by the reference standard does not match the question?			Low concern
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Unclear
Were all patients included in the analysis?	Yes
Could the patient flow have introduced bias?		Low risk