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. 2021 Jul 19;2021(7):CD010772. doi: 10.1002/14651858.CD010772.pub3

Jorm 1991.

Study characteristics
Patient Sampling Participants were recruited as part of a study investigating the reliability and validity of the Canberra Interview for the Elderly (CIE); recruited as a consecutive series. An additional non‐consecutive group were recruited elsewhere (principally psychogeriatricians)
Patient characteristics and setting Patients were a series of those assessed by geriatricians as inpatients, day‐hospital attenders or outpatient clinic attenders (n = 64). As the authors were interested in assessing the score in depression, they also recruited a subgroup of patients, principally via psychogeriatricians (n = 12). Study conducted in Canberra Australia
Index tests IQCODE 26 item, English language
Target condition and reference standard(s) Clinical dementia diagnosis using DSM‐III‐R and ICD‐10
Flow and timing Of 72 potential participants from the geriatric settings 64 agreed to participate. 12 patients were recruited from other sources. Of the 76 potential participants, 7 were excluded due to missing data (index test or MMSE) so total sample was 69.
Reference standard determined by the treating clinician. Index test administered by lay interviewers at an interval afterwards. Unclear if this was blinded to clinical diagnosis. Further index test assessment performed to assess test‐retest reliability
Comparative  
Notes  
Methodological quality
Item Authors' judgement Risk of bias Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled? No    
Was a case‐control design avoided? Yes    
Did the study avoid inappropriate exclusions? Yes    
Could the selection of patients have introduced bias?   High risk  
Are there concerns that the included patients and setting do not match the review question?     High
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition? Yes    
Could the reference standard, its conduct, or its interpretation have introduced bias?   Low risk  
Are there concerns that the target condition as defined by the reference standard does not match the question?     Low concern
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard? Unclear    
Were all patients included in the analysis? Unclear    
Could the patient flow have introduced bias?   High risk