| Study characteristics |
| Patient Sampling |
Participants from the geriatric hospital or memory clinic; sampling frame unclear |
| Patient characteristics and setting |
Participants came from a university hospital in Switzerland. The sample included geriatric patients and those referred to the memory clinic; n = 106, no breakdown by setting |
| Index tests |
IQCODE 16 item, French language |
| Target condition and reference standard(s) |
Clinical dementia diagnosis using DSM‐IV |
| Flow and timing |
Participants underwent cognitive testing and IQCODE assessment prior to assessment using the reference standard. However, the index test was conducted contemporaneously with reference standard. Clinical diagnosis (reference standard) conducted blinded to results of index test |
| Comparative |
|
| Notes |
|
| Methodological quality |
| Item |
Authors' judgement |
Risk of bias |
Applicability concerns |
| DOMAIN 1: Patient Selection |
| Was a consecutive or random sample of patients enrolled? |
Unclear |
|
|
| Was a case‐control design avoided? |
Yes |
|
|
| Did the study avoid inappropriate exclusions? |
Yes |
|
|
| Could the selection of patients have introduced bias? |
|
High risk |
|
| Are there concerns that the included patients and setting do not match the review question? |
|
|
Unclear |
| DOMAIN 3: Reference Standard |
| Is the reference standards likely to correctly classify the target condition? |
Yes |
|
|
| Could the reference standard, its conduct, or its interpretation have introduced bias? |
|
Low risk |
|
| Are there concerns that the target condition as defined by the reference standard does not match the question? |
|
|
Low concern |
| DOMAIN 4: Flow and Timing |
| Was there an appropriate interval between index test and reference standard? |
Yes |
|
|
| Were all patients included in the analysis? |
Yes |
|
|
| Could the patient flow have introduced bias? |
|
Unclear risk |
|
