Narasimhalu 2008.

Study characteristics
Patient Sampling	Patients were obtained from 2 sources: (1) Consecutive referrals to hospital dementia clinic (2) Participants in another study investigating cognition following stroke The study only included those who had completed an MMSE & IQCODE assessment
Patient characteristics and setting	General hospital setting in Singapore; group (1) were referred to the dementia clinic; included 237 out of 695 evaluated. For group (2) 355 included out of 398 who received both tests from 843 total enrolled participants
Index tests	IQCODE 16 item, Cantonese language
Target condition and reference standard(s)	Clinical dementia diagnosis using DSM‐IV
Flow and timing	Unclear order of conduct of the index test and reference standard
Comparative
Notes
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	No
Was a case‐control design avoided?	Yes
Did the study avoid inappropriate exclusions?	No
Could the selection of patients have introduced bias?		High risk
Are there concerns that the included patients and setting do not match the review question?			High
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	Yes
Could the reference standard, its conduct, or its interpretation have introduced bias?		High risk
Are there concerns that the target condition as defined by the reference standard does not match the question?			Unclear
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Unclear
Were all patients included in the analysis?	Unclear
Could the patient flow have introduced bias?		High risk