Siri 2006.

Study characteristics
Patient Sampling	Participants were those referred to a geriatric clinic aged > 60 years, sampling frame unclear
Patient characteristics and setting	Geriatric clinic attenders at a university hospital in Bangkok Thailand. 200 elderly people, divided into 100 'normal' and 100 'demential'
Index tests	IQCODE 32 item, Thai language
Target condition and reference standard(s)	Clinical dementia diagnosis using DSM‐IV
Flow and timing	Participants had to have an informant in order to be eligible. No report of how many potential participants compared with n = 200 (100 'normal', 100 'demential') Assessment of IQCODE conducted blinded to clinical diagnosis
Comparative
Notes
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	No
Was a case‐control design avoided?	Yes
Did the study avoid inappropriate exclusions?	No
Could the selection of patients have introduced bias?		High risk
Are there concerns that the included patients and setting do not match the review question?			Unclear
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	Yes
Could the reference standard, its conduct, or its interpretation have introduced bias?		Low risk
Are there concerns that the target condition as defined by the reference standard does not match the question?			Unclear
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Unclear
Were all patients included in the analysis?	Unclear
Could the patient flow have introduced bias?		High risk