Tang 2003.

Study characteristics
Patient Sampling	Consecutive admissions of first‐ever or recurrent stroke
Patient characteristics and setting	484 were admitted to the Acute Stroke Unit of a general teaching hospital in Hong Kong in the study period; n = 189 included
Index tests	IQCODE 26 item, Chinese language
Target condition and reference standard(s)	Clinical dementia diagnosis using DSM‐IV
Flow and timing	Of 484 potential participants, 471 had an informant available. 95 were excluded due to their response to IQCODE items (> 20% scored 'I don't know'); 17 were excluded due to 'physical frailty' and 18 due to 'prolonged hospitalisation'. IQCODE assessment was performed independently from clinical assessment by a psychiatrist, both were conducted 3 months after index stroke. The clinical assessment was performed in outpatient clinic setting
Comparative
Notes
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	Yes
Was a case‐control design avoided?	Yes
Did the study avoid inappropriate exclusions?	Yes
Could the selection of patients have introduced bias?		Low risk
Are there concerns that the included patients and setting do not match the review question?			High
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	Yes
Could the reference standard, its conduct, or its interpretation have introduced bias?		Low risk
Are there concerns that the target condition as defined by the reference standard does not match the question?			Low concern
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Yes
Were all patients included in the analysis?	No
Could the patient flow have introduced bias?		High risk