Table 4.
Factors affecting zonulin level
| Zonulin level | Test value | p value | ||
|---|---|---|---|---|
| Mean | SD | |||
| Sex | ||||
| Male | 290.11 | 163.89 | 1.12* | 0.27 NS |
| Female | 239.27 | 145.59 | ||
| Residence | ||||
| Urban | 315.55 | 157.34 | 2.51* | 0.02 S |
| Rural | 209.92 | 133.81 | ||
| Age (years) | ||||
| < 30 | 261.67 | 152.41 | 0.15* | 0.88 NS |
| > 30 | 255.00 | 156.83 | ||
| Asthma grade | ||||
| Asthma grade 1 | 127.50 | 8.66 | 64.54** | < 0.001 HS |
| Asthma grade 2 | 209.50 | 103.91 | ||
| Asthma grade 3 | 218.50 | 75.50 | ||
| Asthma grade 4 | 530.00 | 87.83 | ||
| Skin prick | ||||
| Negative | 299.29 | 182.05 | 1.20* | 0.24 NS |
| Positive | 241.47 | 138.88 | ||
| Zonulin level | ||||
| Total IgE | ||||
| Pearson correlation | 0.14 | |||
| p value | 0.34NS | |||
*Student t test
**One Way ANOVA test (post hoc test shows significant difference between grade 1 vs grade 2, grade 1 vs grade 3, grade 1 vs grade 4, grade 2 vs grade 4 and grade 3 vs grade 4)
NS, Non-significant; S, Significant; HS, Highly significant