Comparison 12. Primary health professional‐led or collaborative care versus specialist‐led care for people with severe mental disorders.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
12.1 Clinical recovery from severe mental disorders	1	76	Risk Ratio (M‐H, Random, 95% CI)	1.08 [0.81, 1.44]
12.1.1 Short term (up to 1 month post intervention)	1	76	Risk Ratio (M‐H, Random, 95% CI)	1.08 [0.81, 1.44]
12.2 Relapse of severe mental disorders	4	492	Risk Ratio (M‐H, Random, 95% CI)	0.30 [0.16, 0.55]
12.2.1 Short term (up to 1 month post intervention)	4	492	Risk Ratio (M‐H, Random, 95% CI)	0.30 [0.16, 0.55]
12.3 Schizophrenia symptoms	6		Std. Mean Difference (IV, Random, 95% CI)	Subtotals only
12.3.1 Short term (up to 1 month post intervention)	6	836	Std. Mean Difference (IV, Random, 95% CI)	‐0.30 [‐0.71, 0.11]
12.4 Depression symptoms	2		Std. Mean Difference (IV, Random, 95% CI)	Subtotals only
12.4.1 Short term (up to 1 month post intervention)	2	270	Std. Mean Difference (IV, Random, 95% CI)	‐0.41 [‐1.13, 0.32]
12.5 Quality of life	3		Std. Mean Difference (IV, Random, 95% CI)	Subtotals only
12.5.1 Short term (up to 1 month post intervention)	3	536	Std. Mean Difference (IV, Random, 95% CI)	0.40 [‐0.37, 1.17]
12.6 Functional impairment	7		Std. Mean Difference (IV, Random, 95% CI)	Subtotals only
12.6.1 Short term (up to 1 month post intervention)	7	874	Std. Mean Difference (IV, Random, 95% CI)	‐1.13 [‐1.78, ‐0.47]
12.7 Service utilisation ‐ hospital re‐admission (1 year from randomisation)	3	441	Risk Ratio (M‐H, Random, 95% CI)	0.60 [0.28, 1.28]