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. 2001 Jan 22;2001(1):CD001518. doi: 10.1002/14651858.CD001518

Comparison 1. Cabergoline versus Placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 UPDRS ADL scores (part II)     Other data No numeric data
2 UPDRS motor score (part III)     Other data No numeric data
3 Hoehn and Yahr stage     Other data No numeric data
4 Schwab and England scale     Other data No numeric data
5 Clinicians global impression scale     Other data No numeric data
6 Levodopa dose reduction (mg) 1 188 Mean Difference (IV, Fixed, 95% CI) 149.6 [94.12, 205.08]
7 Off time reduction (hours) 2 61 Mean Difference (IV, Fixed, 95% CI) 1.14 [‐0.06, 2.33]
8 Dyskinesia rating scale     Other data No numeric data
9 Adverse events ‐ Nausea 3 268 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.84 [0.97, 3.49]
10 Adverse events ‐ Postural hypotension 3 268 Peto Odds Ratio (Peto, Fixed, 95% CI) 2.28 [1.11, 4.69]
11 Adverse events ‐ Hallucinations 3 268 Peto Odds Ratio (Peto, Fixed, 95% CI) 2.08 [0.77, 5.57]
12 Adverse events ‐ Confusion 3 268 Peto Odds Ratio (Peto, Fixed, 95% CI) 3.73 [1.02, 13.67]
13 Adverse events ‐ Dyskinesia 1 43 Peto Odds Ratio (Peto, Fixed, 95% CI) 6.49 [0.13, 329.99]
14 Adverse events ‐ Insomnia 2 225 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.00 [0.46, 2.15]
15 Adverse events ‐ Sleep disorder 1 188 Peto Odds Ratio (Peto, Fixed, 95% CI) 4.61 [0.07, 284.12]
16 Adverse events ‐ Somnolence 2 231 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.63 [0.48, 5.48]
17 All cause withdrawal rate 3 268 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.58 [0.28, 1.18]