2. AMSTAR scores: NRT, antidepressants and nicotine receptor partial agonists.

Question	Nicotine Replacement Therapy	Bupropion	Nicotine receptor partial agonists
1.A priori design provided?	CAN'T ANSWER	CAN'T ANSWER	YES
2. Duplicate study selection and data extraction?	YES	YES	YES
3. Comprehensive literature search performed?	YES	YES	YES
4. Published and unpublished studies included?	YES	YES	YES
5. List of included and excluded studies?	YES	YES	YES
6. Characteristics of included studies provided?	YES	YES	YES
7. Scientific quality of included studies assessed?	YES	YES	YES
8. Scientific quality of included studies applied to conclusions?	YES	YES	YES
9. Appropriate methods for combining studies?	YES	YES	YES
10. Likelihood of publication bias?	YES	NO	NO
11. Conflict of interest stated?	YES	YES	YES
SCORE	10/11	9/11	10/11