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| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 Failed to recover | 1 | 57 | Risk Ratio (M‐H, Random, 95% CI) | 1.59 [1.07, 2.35] |
| 2 Depression severity (HAM‐D Scale) | 1 | 25 | Mean Difference (IV, Fixed, 95% CI) | 6.00 [‐0.34, 12.34] |
| 3 Withdrawal due to side effects | 4 | 174 | Risk Ratio (M‐H, Random, 95% CI) | 1.07 [0.43, 2.70] |
| 4 Total withdrawal rates | 4 | 174 | Risk Ratio (M‐H, Random, 95% CI) | 1.49 [0.74, 2.98] |
