Smeraldi 1998.

Methods	Double blind RCT. Concealment of allocation ‐ unclear. Analysis: Endpoint Active treatment: 6 weeks
Participants	Inclusion criteria: DSM IIIR, Major Depressive disorder for at least 1 month and 22+ MADRS Age:Over 65 Country: Italy Setting: Geriatric Inpatients + Outpatients
Interventions	Venlafaxine versus clomipramine versus trazodone
Outcomes	Side effects Drop out
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear