Table 3.

Modified Mankin score for evaluation of articular cartilage degeneration as described by Henson and Vincent [32]

Score	Structure	Cellularity	Matrix staining	Tidemark integrity
Score 0	Smooth surface	Normal arrangement	Normal staining	Normal and intact
	Normal appearance
Score 1	Roughened surface	Clustering in the superficial layer or loss of cells up to 10%	Slight loss of stain	Disrupted
	Single crack or area of delamination
Score 2	Multiple cracks	Disorganization or loss up to 25%	Moderate loss of stain
	Moderate delamination
Score 3	Fragmentation in cartilage or severe delamination	Cell rows absent or loss up to 50%	Severe loss of stain
Score 4	Loss of fragments	Very few cells present	No stain present
Score 5	Complete erosion to tidemark
Score 6	Erosion beyond tidemark