Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 12;11:699749. doi: 10.3389/fonc.2021.699749

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Yao, He, Gao, Tang, Lin, Yu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

METTL14 inhibits STAD cells proliferation and invasion via regulation of PTEN. (A, B) METTL14 overexpression inhibits HGC-27 and AGS cells growth, and targeting PTEN by VO-Ohpic antagonized the effect of METTL14 inhibiting the growth of HGC-27 and AGS cells. (C, D) METTL14 overexpression inhibits HGC-27 and AGS cells invasion. When METTL14 overexpression and treatment of VO-Ohpic in HGC-27 and AGS cells, the invasive abilities of HGC-27 and AGS cells after METTL14 overexpression was enhanced by VO-Ohpic. (**P < 0.01; ***P < 0.001; ns, no significant difference).