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. 2021 Jul 17:btab533. doi: 10.1093/bioinformatics/btab533

Fig. 3.

Fig. 3.

(a) Overlap of experimentally observed and predicted interactions between proteins of the human host and SARS-CoV-2. (b) In a quantitative functional analysis of targeted human host proteins, we considered the enrichment of GO terms and KEGG pathways through a hypergeometric test (Bonferroni corrected P-value 0.01). We found that a relatively large share of functional terms in groups of host proteins appearing in the experimentally known PPIs and predictions. (c) In more detail, we observed that enriched GO BP terms in host proteins appearing in the experimental and predicted PPIs were functionally similar