Table 3.

Multivariable analysis using the variables included in the final model

Variables in the final model	OR *	p-value	95% CI
Sex (Female)	1.78	0.017	1.11–2.84
N° of metastatic sites	0.82	0.033	0.68–0.98
Adrenal metastases (Yes)	0.43	0.051	0.18–1.00
CNS metastases (Yes)	0.45	0.016	0.24–0.86
ECOG (≥2)	0.20	< 0.001	0.10–0.40
Exon 20 insertion (Yes)	0.36	0.060	0.13–1.05
Liver metastases (Yes)	0.52	0.063	0.27–1.04
Constant	2.77	< 0.001	1.64–4.69

* OR: Odds Ratio; 95% CI: Confidence interval. The maximum model included: sex, age, smoking history, stage, ECOG, weight loss, Exon 19 deletion, Exon 20 insertion, liver metastases, CNS metastases, adrenal metastases, N° of metastatic sites