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. 2015 Jul 14;2015(7):CD007614. doi: 10.1002/14651858.CD007614.pub2

5. Measurement of coagulation: prothrombin time (PT).

  FFP Comparator
Kasper 2001 ‐ percentage of expected prothrombin time after FFP (or comparator) infusion* 58% ± 10%
(n = 27)		 46% ± 8%
(n = 29)
Kyoung 2004 ‐ international normalised ratio at end of surgery* 1.44 ± 0.13
(n = 10)		 2.01 ± 0.42
(n = 10)
Lee 2013 ‐ prothrombin time after 24 hours in ICU: infants** 15.3 seconds (14 to 16.1 seconds)
(n = 26)		 14.8 seconds (13.7 to 16.6 seconds)
(n = 28)
Lee 2013 ‐ prothrombin time after 24 hours in ICU: children (aged 1 to 16 years)* 15 seconds ± 1.7 seconds
(n = 34)		 15 seconds ± 1.9 seconds
(n = 33)
Wilhelmi 2001 ‐ percentage of expected prothrombin time after admission to ICU* 79% ± 9.3%
(n = 60)		 74% ± 10.1%
(n = 60)

*Data reported as mean ± standard deviation.
**Data reported as median (interquartile range).

FFP: fresh frozen plasma
ICU: intensive care unit