1. Overview of study populations.
Characteristic Study ID |
Intervention(s) and control(s) | [N] screened | [N] randomised | [N] safety | [N] ITT | [N] finishing study | [%] of randomised participants finishing study |
Auvichayapat 2008 1 (weight loss study) | I1: green tea extract C1: placebo |
I1: ‐ C1: ‐ T: 73 |
I1: 30 C1: 30 T: 60 |
I1: 30 C1: 30 T: 60 |
‐ | I1: 30 C1: 30 T: 60 |
I1: 100 C1: 100 T: 100 |
Diepvens 2005 (weight loss study) | I1: green tea C1: placebo |
I1: ‐ C1: ‐ T: 57 |
I1: 23 C1: 23 T: 46 |
I1: 23 C1: 23 T: 46 |
‐ | I1: 23 C1: 23 T: 46 |
I1: 100 C1: 100 T: 100 |
Hill 2007 (weight loss study) | I1: green tea extract C1: placebo |
‐ | I1: ‐ C1: ‐ T: 42 |
I1: ‐ C1: ‐ T: 42 |
‐ | I1: 19 C1: 19 T: 38 |
I1: ‐ C1: ‐ T: 91 |
Hsu 2008 (weight loss study) | I1: green tea extract C1: placebo |
I1: ‐ C1: ‐ T: 336 |
I1: 50 C1: 50 T: 100 |
‐ | ‐ | I1: 41 C1: 37 T: 78 |
I1: 82 C1: 74 T: 78 |
Hursel 2009 (weight maintenance study) | I1: green tea‐caffeine mixture + AP diet I2: green tea‐caffeine mixture + HP diet C1: placebo + AP diet C2: placebo + HP diet |
I1: ‐ I2: ‐ C1: ‐ C2: ‐ T: 100 |
I1: 20 I2: 20 C1: 20 C2: 20 T: 80 |
I1: 20 I2: 20 C1: 20 C2: 20 T: 80 |
‐ | I1: 20 I2: 20 C1: 20 C2: 20 T: 80 |
I1: 100 I2: 100 C1: 100 C2: 100 T: 100 |
Kajimoto 2005 (weight loss study) | I1: catechin drink – low‐dose group I2: catechin drink – high‐dose group C1: placebo drink |
‐ | I1: ‐ I2: ‐ C1: ‐ T: 197 |
I1: ‐ I2: ‐ C1: ‐ T: 197 |
‐ | I1: 65 I2: 64 C1: 66 T: 195 |
I1: ‐ I2: ‐ C1: ‐ T: 99 |
Kataoka 2004 (weight loss study) | I1: catechin beverage 278 mg I2: catechin beverage 570 mg I3: catechin beverage 845 mg C1: control beverage |
‐ | I1: 25 I2: 71 I3: 25 C1: 71 T: 192 |
I1: 25 I2: 71 I3: 25 C1: 71 T: 192 |
‐ | I1: 25 I2: 71 I3: 25 C1: 71 T: 192 |
I1: 100 I2: 100 I3: 100 C1: 100 T: 100 |
Kovacs 2004 2 (weight maintenance study) | I1: green tea C1: placebo |
I1: ‐ C1: ‐ T: 140 |
I1: ‐ C1: ‐ T: 120 |
I1: 51 C1: 53 T: 104 |
‐ | I1: 51 C1: 53 T: 104 |
I1: ‐ C1: ‐ T: 87 |
Kozuma 2005 3 (weight loss study) | I1: catechin beverage C1: placebo beverage |
I1: ‐ C1: ‐ T: 254 |
I1: ‐ C1: ‐ T: 234 |
I1: ‐ C1: ‐ T: 234 |
‐ | I1: 107 C1: 119 T: 226 |
I1: ‐ C1: ‐ T: 97 |
Maki 2009 4 (weight loss study) | I1: green tea beverage C1: control beverage |
I1:‐ C1:‐ T: 337 |
I1: 67 C1: 65 T: 132 |
I1: 66 C1: 63 T: 129 |
I1: 65 C1: 63 T: 128 |
I1: 56 C1: 51 T: 107 |
I1: 84 C1: 79 T: 81 |
Nagao 2007 (weight loss study) | I1: brewed green tea beverage with added catechins C1: brewed green tea beverage with no added catechins |
‐ | I1: 135 C1: 135 T: 270 |
‐ | ‐ | I1: 123 C1: 117 T: 240 |
I1: 91 C1: 87 T: 89 |
Suzuki 2009 (weight loss study) | I1: tea catechin C1: placebo |
‐ | I1: 20 C1: 21 T: 41 |
‐ | ‐ | I1: 18 C1: 20 T: 38 |
I1: 90 C1: 95 T: 93 |
Takase 2008 5 (weight loss study) | I1: catechin beverage C1: placebo beverage |
‐ | I1: 49 C1: 52 T: 101 |
I1: 48 C1: 46 T: 94 |
‐ | I1: 46 C1: 47 T: 93 |
I1: 94 C1: 90 T: 92 |
Takashima 2004 (weight loss study) | I1: catechin beverage C1: control beverage |
‐ | I1: 10 C1: 9 T: 19 |
I1: 10 C1: 9 T: 19 |
‐ | I1: 10 C1: 9 T: 19 |
I1: 100 C1: 100 T: 100 |
Takeshita 2008 (weight loss study) | I1: catechin beverage C1: placebo beverage |
‐ | I1: 40 C1: 41 T: 81 |
I1: 40 C1: 41 T: 81 |
‐ | I1: 40 C1: 41 T: 81 |
I1: 100 C1: 100 T: 100 |
Tsuchida 2010 (weight loss study) | I1: catechin beverage C1: control beverage |
‐ | I1: 39 C1: 41 T: 80 |
I1: 39 C1: 41 T: 80 |
‐ | I1: 39 C1: 41 T: 80 |
I1: 100 C1: 100 T: 100 |
Wang 2010 6 (weight loss study) | I1: green tea 1 I2: green tea 2 I3: green tea 3 C1: control drink |
I1: ‐ I2: ‐ I3: ‐ C1: ‐ T: 435 |
I1: ‐ I2: ‐ I3: ‐ C1: ‐ T: 205 |
‐ | ‐ | I1: ‐ I2: ‐ I3: ‐ C1: ‐ T: 192 |
I1: ‐ I2: ‐ I3: ‐ C1: ‐ T: 94 |
Westerterp‐Plantenga 2005 (weight maintenance study) | I1: green tea‐caffeine capsule ‐ low habitual caffeine consumers I2: green tea‐caffeine capsule ‐ high habitual caffeine consumers C1: placebo ‐ low habitual caffeine consumers C2: placebo ‐ high habitual caffeine consumers |
I1: ‐ I2: ‐ C1: ‐ C2: ‐ T: 90 |
I1: 19 I2: 19 C1: 19 C2: 19 T: 76 |
I1: 19 I2: 19 C1: 19 C2: 19 T: 76 |
‐ | I1: 19 I2: 19 C1: 19 C2: 19 T: 76 |
I1: 100 I2: 100 C1: 100 C2: 100 T: 100 |
Total7 | Weight loss studies | 1800 | 1685 | ||||
Weight maintenance studies | 276 | 260 | |||||
All studies | 2076 | 1945 |
"‐" denotes not reported. 1 all participants were Khon Kaen University officers. 2 this was a two‐part study. Participants were given special diet (not including green tea) to lose weight for four weeks. They were then given green tea to see if it would help maintain weight loss. Sixteen participants dropped out during very‐low‐energy diet period before ever receiving the intervention or placebo. 3 254 participants "gave informed consent" – it is not clear if this was the actual number screened, but we think so. 4 this study's usage of ITT differs from the Cochrane definition. 5 "of these individuals, four whose insulin levels recorded at week 0 were abnormal (two in the placebo group and two in the catechin group) were excluded from analysis, leaving a group suitable for analysis of 45 individuals in the placebo group and 44 individuals in the catechin group." 6 although 192 completed the study 10 participants were excluded from analysis for various reasons; thus analysis was carried out for 182 participants. 7 not all studies specified how many participants were randomised into each group at the start, though totals are available for each study. In one case (Wang 2010), the number of participants in each group at the end of the study was also not given, though the total number of participants finishing was given.
C: control; I: intervention; ITT: intention to treat; T: total.