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. 2012 Dec 12;2012(12):CD008650. doi: 10.1002/14651858.CD008650.pub2
Characteristic
Study ID
Intervention(s) and control(s) Primarya end point(s) Secondarya 
 end point(s)  Otherb end point(s)
Auvichayapat 2008 I1:   green tea extract
C1: placebo
Average left capsule (%) 
 Blood pressure
BMI 
 Body fat % 
 Diastolic blood pressure 
 Food intake 
 Heart rate 
 Height 
 Hip circumference 
 Leptin 
 Physical activity 
 Respiratory quotient 
 Resting energy expenditure 
 Satiety 
 Systolic blood pressure 
 Substrate oxidation 
 Urine vanillylmandelic acid 
 Waist circumference 
 Waist‐to‐hip ratio 
 Weight
Diepvens 2005 I1: green tea
C1: placebo
Appetite ratings 
 Attitudes towards eating 
 BMI 
 Body fat % 
 Caffeine intake 
 Carbohydrate oxidation 
 Cognitive restraint 
 Diastolic blood pressure 
 Disinhibition 
 Eating behaviour (restrained/unrestrained) 
 Emotional eating 
 Energy expenditure 
 Fat free mass 
 Fat mass 
 Fat oxidation 
 Heart rate 
 Height 
 Hip circumference 
 Hunger 
 Mood 
 Respiratory quotient (post‐absorptive) 
 Respiratory quotient (post‐prandial) 
 Resting energy expenditure 
 Systolic blood pressure 
 Tolerance of treatment 
 Total body water 
 Waist circumference 
 Waist‐to‐hip ratio 
 Weight
Hill 2007 I1: green tea extract
C1: placebo
Abdominal fat 
 Adipocytokines 
 Adiponectin 
 Blood lipids 
 Blood pressure (resting) 
 BMI 
 Body composition 
 Body fat mass 
 Body fat percentage 
 Body lean mass 
 Diastolic blood pressure 
 Direct glyceryl trinitrate‐induced vasodilation 
 Endothelium‐dependent flow‐mediated dilation 
 Energy expenditure 
 Energy intake 
 Flow‐mediated dilation 
 Follicle stimulating hormone 
 Fructosamine 
 Glucose 
 Glyceryl trinitrate‐mediated dilation 
 Haematology 
 Heart rate 
 Height 
 Hip circumference 
 Insulin 
 Intra‐abdominal adipose tissue 
 Large artery compliance 
 Leptin 
 Liver function 
 Serum electrolytes 
 Small artery compliance 
 Subcutaneous adipose tissue 
 Systolic blood pressure 
 Total body fat 
 Visceral fat area 
 Waist circumference 
 Waist‐to‐hip ratio 
 Weight
Hsu 2008 I1: green tea extract
C1:  placebo
Note: "The outcome was evaluated 
 as % reduction in BW, BMI and WC 
 after 12 weeks of intervention"
The word "primary" was not used
Adiponectin 
 Aminotransferase alanine 
 Aminotransferases aspartate 
 Blood sugar 
 BMI 
 Cholesterol 
 Creatinine 
 Ghrelin 
 Glucose 
 HDL‐cholesterol 
 Height 
 Hip circumference 
 HOMA insulin resistance index 
 Insulin 
 LDL‐cholesterol 
 Leptin 
 Triglyceride 
 Uric acid 
 Waist circumference 
 Weight
Hursel 2009 I1: green tea‐caffeine mixture + AP diet
I2: green tea‐caffeine mixture + HP diet
C1: placebo + AP diet
C2: placebo + HP diet 
Attitudes towards eating 
 Beta‐hydroxybutyrate 
 BMI 
 Body fat distribution 
 Fat free mass 
 Fat mass 
 Free fatty acid concentrations 
 Glucose 
 Glycerol concentrations 
 Height 
 Hunger 
 Insulin 
 Leptin 
 Physical activity level 
 Post‐absorptive appetite profile *(VAS ) 
 Respiratory quotient 
 Resting energy expenditure 
 Satiety 
 Substrate oxidation 
 Total body water 
 Total energy expenditure 
 Triacylglycerol 
 Waist circumference 
 Weight
Kajimoto 2005 I1: catechin drink – low dose group
I2: catechin drink – high dose group
C1: placebo drink
Adverse events 
 Alanine aminotransferase 
 Albumin 
 Alcohol intake 
 Alkaline phosphatase 
 Amylase 
 Aspartate aminotransferase 
 BMI 
 Calcium 
 Carbohydrate intake 
 Chloride 
 Chlorine 
 Cholesterol intake 
 Cholinesterase 
 Creatinine 
 Creatinine phosphokinase 
 Dietary fibre intake 
 Direct bilirubins 
 Energy intake 
 Erythrocytes 
 Fasting glucose level 
 Fat intake 
 Ferritin 
 Gamma‐glutamyl transpeptidase 
 Glucose 
 Glycated haemoglobin 
 HDL‐cholesterol 
 Height 
 Haematocrit 
 Haemoglobin 
 Hip circumference 
 Inorganic Phosphate 
 Insulin 
 Iron 
 Ketone body fractions 
 Lactate dehydrogenase 
 LDL‐cholesterol 
 Leukocytes 
 Magnesium 
 Physical activity levels 
 Platelet counts 
 Potassium 
 Protein intake 
 Sodium 
 Subcutaneous fat area 
 Total bilirubins
Total cholesterol 
 Total fat area 
 Total proteins 
 Triacylglycerol 
 Unsaturated iron binding capacity 
 Urea nitrogen 
 Uric acid 
 Visceral fat area (VFA) 
 Waist circumference 
 Waist‐to‐hip ratio 
 Weight
Kataoka 2004 I1: catechin beverage 278 mg
I2: catechin beverage 570 mg
I3: catechin beverage 845 mg
C1: control
beverage
Abdominal fat area 
 Albumin 
 Alkaline phosphatase 
 Blood sugar 
 Blood urea nitrogen 
 BMI 
 Body fat ratio 
 Calcium 
 Chloride 
 Creatinine 
 Energy intake 
 Fat intake 
 Free fatty acid 
 Gamma‐glutamyl transpeptidase 
 GOT 
 GPT 
 HDL cholesterol 
 Height 
 Haematocrit 
 Haemoglobin 
 Hip circumference 
 Inorganic phosphate 
 Iron 
 Lactate dehydrogenase 
 LDL cholesterol 
 Magnesium 
 Number of steps 
 Platelet count 
 Potassium 
 Red blood cell count 
 Sodium 
 Subcutaneous fat area 
 Total cholesterol 
 Total fat area 
 Total plasminogen activator inhibitor‐1 
 Total protein 
 Triacylglycerol 
 Uric acid 
 Visceral fat area 
 Waist circumference 
 Weight 
 White blood cell count
Kovacs 2004 I1: green tea
C1: placebo
Adverse events 
 Attitude towards eating 
 Beta‐hydroxybutyrate 
 BMI 
 Body fat % 
 Caffeine intake 
 Cognitive restraint 
 Disinhibition 
 Fat free mass 
 Fat mass 
 Frequency of previous dieting 
 Glucose 
 Glycerol concentrations 
 Height 
 Hip circumference 
 Hunger 
 Insulin 
 Leptin 
 Non‐esterified fatty acids 
 Physical activity level 
 Post‐absorptive appetite profile 
 Respiratory quotient 
 Resting energy expenditure 
 Satiety 
 Substrate oxidation 
 Total body water 
 Total energy expenditure 
 Triacylglycerol 
 Waist circumference 
 Waist‐to‐hip ratio 
 Weight
Kozuma 2005 I1: catechin beverage
C1: placebo beverage
Acetoacetic acid 
 Alanine aminotransferase 
 Albumin 
 Alkaline phosphatase 
 Aspartate aminotransferase 
 Beta‐hydroxybutyric acid 
 Blood sugar 
 Blood urea nitrogen 
 BMI 
 Body fat 
 Calcium 
 Chloride 
 Creatinine 
 Diastolic blood pressure 
 Fasting blood sugar 
 Gamma‐glutamyl transpeptidase 
 HDL‐cholesterol 
 Height 
 Haematocrit 
 Haemoglobin 
 Hip circumference 
 Inorganic phosphate 
 Iron 
 Lactate dehydrogenase 
 LDL cholesterol 
 Magnesium 
 Non‐esterfied fatty acid 
 Platelet counts 
 Potassium 
 Pulse rate 
 Red blood cells 
 Remnant lipoprotein cholesterol 
 Sodium 
 Subcutaneous fat area 
 Systolic blood pressure 
 Total cholesterol 
 Total fat area 
 Total proteins 
 Triglycerides 
 Uric acid 
 Urine ketone bodies 
 Urine protein 
 Urine sugar 
 Urine urobilinogen 
 Visceral fat area 
 Waist circumference 
 Weight 
 White blood cells
Maki  2009 I1: green tea beverage
C1: control beverage
Abdominal fat areas 
 Beta‐hydroxybutyrate 
 Blood pressure 
 Body composition 
 Caffeine intake 
 Insulin (fasting) 
 Free fatty acids 
 Glucose (fasting) 
 High‐sensitivity C‐reactive protein (hs‐CRP) 
 Intra‐abdominal fat area 
 MDA (plasma concentration) 
 Maximal treadmill exercise testing 
 Metabolic equivalent hours (MET‐hours) 
 Pedometer readings 
 Plasma high‐sensitivity C‐reactive protein 
 (hs‐CRP) 
 Serum FFA 
 Serum HDL‐cholesterol 
 Serum LDL‐cholesterol 
 Serum lipids 
 Serum total‐C concentrations 
 Subcutaneous fat area 
 Total fat mass 
 Triglyceride concentrations 
 Waist circumference 
 Weight 
 Whole blood glycosylated haemoglobin
Nagao 2007 I1: brewed green tea beverage 
 with added catechins
C1: brewed green tea beverage 
 with no added catechins
Abdominal fat level 
 Alkaline phosphatase 
 BMI 
 Body fat mass 
 Body fat ratio 
 Caffeine intake from tea and coffee 
 Coffee intake 
 Computed tomography scan 
 Diastolic blood pressure 
 Energy intake based on food intake 
 Fat energy ratio 
 Fat intake 
 Free fatty acids 
 Gamma glutamyl transferase 
 Gamma glutamyl transpeptidase 
 Glucose 
 Glutamic‐oxaloacetic transaminase 
 Glutamic‐pyruvic transaminase 
 HDL cholesterol 
 Height 
 Haematocrit values 
 Haemoglobin 
 Hip circumference 
 Lactate dehydrogenase 
 LDL cholesterol 
 Lean body mass 
 Platelets 
 Pulse rate 
 Red blood cell count 
 Serum triacylglycerol 
 Subcutaneous fat area 
 Systolic blood pressure 
 Tannin intake from tea and coffee 
 Tea intake 
 Total cholesterol 
 Total fat area 
 Visceral fat area 
 Waist circumference 
 Weight 
 White blood cell count
Suzuki 2009 I1: tea catechin
C1: placebo
Abdominal fat area 
 Alcohol intake 
 BMI 
 Energy intake 
 HDL cholesterol 
 Height 
 Hip circumference 
 LDL cholesterol 
 Number of steps 
 Observable symptoms 
 Patient complaints 
 Remnant lipoprotein cholesterol 
 Small dense LDL 
 Subcutaneous fat area 
 Total cholesterol 
 Total fat area 
 Triglycerides 
 Visceral fat area 
 Waist circumference 
 Weight
Takase 2008 I1: catechin beverage
C1: placebo beverage
Acetic acid 
 Albumin 
 Alkaline phosphatase 
 Aspartate aminotransferase 
 Beta‐hydroxybutyric acid 
 BMI 
 Calcium 
 Calories 
 Carbohydrate (% of energy) 
 Chlorine 
 Cholesterol (total) 
 Creatine 
 Diastolic blood pressure 
 Energy intake based on food intake 
 Fasting blood sugar 
 Fat intake 
 Fibre 
 Free fatty acids 
 Gamma‐glutamyl transpeptidase
HDL cholesterol
Height
Haematocrit values
Haemoglobin
Hip circumference
Inorganic phosphate
Insulin 
 Iron 
 ketone bodies (total) 
 Lactate dehydrogenase 
 LDL cholesterol 
 Magnesium 
 Neutral fats 
 Nutritional content of food intake 
 Platelets 
 Potassium  
 protein (total) 
 Protein intake 
 Red blood cell count 
 Sodium 
 Subcutaneous fat area 
 Systolic blood pressure 
 Total fat area 
 Triglycerides 
 Urea nitrogen 
 Uric acid 
 Urine glucose 
 Urine ketones 
 Urine protein 
 Urobilinogen 
 Visceral fat area 
 Waist circumference 
 Weight 
 White blood cell count
Takashima 2004 I1: catechin beverage
C1: control beverage
Abdominal fat area 
 Blood sugar 
 BMI 
 Body fat ratio 
 Carbohydrate oxidation 
 CO2 consumption 
 Energy expenditure 
 Exercise tolerance 
 Fat free mass 
 Fat oxidation 
 Free fatty acid 
 Height 
 Haematocrit 
 Haemoglobin 
 Hip circumference 
 Insulin 
 Ketone body 
 Lactic acid 
 Number of daily steps 
 Oxygen consumption 
 Red blood cell count 
 Respiratory exchange ratio 
 Respiratory quotient 
 Resting energy expenditure 
 Subcutaneous fat area 
 Total energy expenditure 
 Total fat area 
 Visceral fat area 
 Waist circumference 
 Weight
Takeshita 2008 I1: catechin beverage
C1: placebo beverage
Note: "Measurement of the key factor of 
 interest, the amount of abdominal fat 
 (area of abdominal fat), occurred at the 
 beginning of the study (baseline) and at 
 its completion (the 12th week)" 
 The word “primary” was not used Abdominal fat 
 Alanine aminotransferase 
 Albumin 
 Alcohol intake (g/d) 
 Alkaline phosphatase 
 Aspartate aminotransferase 
 Blood pressure 
 Blood urea nitrogen 
 BMI 
 Body fat mass 
 Body fat ratio 
 Calcium 
 Carbohydrate (% of energy) 
 Chlorine 
 Cholesterol 
 Coffee intake (mg caffeine/d) 
 Coffee intake (mL/d) 
 Creatinine 
 Diastolic blood pressure 
 Dietary fibre (g/d) 
 Dietary intake 
 Energy (kcal/d) 
 Fat (% of energy) 
 Free fatty acids 
 Gamma‐glutamyltranspeptidase 
 Glucose 
 Height 
 Haematocrit 
 Haemoglobin 
 HDL‐cholesterol 
 Hip circumference 
 Inorganic phosphate 
 Insulin 
 Intake of beverage 
 Iron 
 How they were feeling 
 Ketone bodies 
 Lactate dehydrogenase 
 LDL cholesterol 
 Lean body mass 
 Magnesium 
 Neutral fat 
 Pedometer steps (steps/d) 
 Plasma glucose 
 Platelets 
 Potassium 
 Protein (% of energy) 
 Pulse rate 
 Red blood cells 
 Safety parameters 
 Side effects 
 Sodium 
 State of health 
 Subcutaneous fat area 
 Systolic blood pressure 
 Tannin intake from coffee (mg/d) 
 Total cholesterol 
 Total fat area 
 Triacylglycerol 
 Unsaturated iron‐binding capacity 
 Uric acid 
 Urine ketone bodies 
 Urea nitrogen 
 Urine protein 
 Urine sediment 
 Urine sugar 
 Urine urobilinogen 
 Visceral fat area 
 Waist circumference 
 Weight 
 White blood cells
Tsuchida 2010 I1: catechin beverage
C1: control beverage
Albumin 
 Alkaline phosphatase 
 Blood sugar 
 Body fat mass 
 Body fat ratio 
 BMI 
 Calcium 
 Chloride 
 Creatinine 
 Diastolic blood pressure 
 Energy intake 
 Fat energy ratio 
 Fat intake 
 Free fatty acids 
 Gamma‐glutamyl transpeptidase 
 Glucose 
 GOT 
 GPT 
 HDL‐cholesterol 
 Heart rate 
 Height 
 Haematocrit 
 Haemoglobin 
 Hip circumference 
 Inorganic phosphate 
 Iron 
 Ketone bodies 
 Lactate dehydrogenase 
 LDL cholesterol 
 Lean body mass 
 Magnesium 
 Phospholipids 
 Platelet counts 
 Potassium 
 Protein 
 Red blood cells 
 Sodium 
 Subcutaneous fat area 
 Systolic blood pressure 
 Total cholesterol 
 Total fat area 
 Total plasminogen activity inhibitor‐1 
 Total protein 
 Triglyceride 
 Urea nitrogen 
 Uric acid 
 Urine glucose 
 Urine ketone bodies 
 Urine protein 
 Urine urobilinogen 
 Visceral fat area 
 Waist circumference 
 Waist‐to‐hip ratio 
 Weight 
 White blood cells
Wang 2010 I1: GT1
I2: GT2
I3: GT3
C1: C
Note: “The response variable of main 
 interest was body weight.” 
 The word "primary was not used. Alanine aminotransferase 
 Alkaline phosphatase 
 Aspartate aminotransferase 
 Blood glucose 
 BMI 
 Body fat % 
 Dietary habits 
 Energy intake 
 Fat mass 
 Gamma‐glutamyltransferase 
 Glucose 
 HDL cholesterol 
 Height 
 Hip circumference 
 Intra‐abdominal fat 
 Lactate dehydrogenase 
 LDL cholesterol 
 Lean mass 
 Lifestyle habits 
 Product liking 
 Sagittal diameter 
 Self‐perceived health status 
 Total cholesterol 
 Triglycerides 
 Waist circumference 
 Weight 
 Whole body fat mass
Westerterp‐
Plantenga 2005
I1: green tea‐caffeine capsule 
 ‐ low habitual caffeine consumers
I2: green tea‐caffeine capsule 
 ‐ high habitual caffeine consumers
C1: placebo 
 ‐ low habitual caffeine consumers
C2: placebo 
 ‐ high habitual caffeine consumers
adverse effects 
 Attitude towards eating 
 Beta‐hydroxybutyrate 
 BMI 
 Body fat % 
 Caffeine intake 
 Cognitive restraint 
 Disinhibition 
 Fat distribution 
 Fat free mass 
 Fat mass 
 Free fatty acids 
 Frequency of previous dieting 
 Glucose 
 Glycerol 
 Height 
 Hunger 
 Insulin 
 Leptin 
 Physical activity level 
 Respiratory quotient 
 Resting energy expenditure 
 Satiety 
 Substrate oxidation 
 Total body water 
 Total energy expenditure 
 Triacylglycerol 
 Triglycerides 
 Waist circumference 
 Weight
Footnotes
"‐" denotes not reported
aAs stated in the publication 
 bNot stated as primary or secondary end point(s) in the publication
AP: adequate protein; BMI: body mass index; CO2: carbon dioxide; C: control; GOT: glutamic oxalacetic transaminase; GPT: glutamic‐pyruvic transaminase; GT: green tea; HP: high protein; HOMA: homeostasis model assessment; I: intervention; VAS: visual analogue scale